Bridging non-overlapping reads illuminates high-order epistasis between distal protein sites in a GPCR

Bridging non-overlapping reads illuminates high-order epistasis between distal protein sites in a GPCR

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Epistasis effects among amino acids at distal sites within binding pockets can Toaster have important impacts on protein fitness landscapes.Here the authors present BRIDGE, which matches non-overlapping sequence reads Inline - Wheels Court with their cognate DNA templates.